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Certified.
Science-backed results published and endorsed by:
Simple and private—from start to finish.
Sapyen was developed by leading clinicians.
Designed alongside clinics, including:
Sapyen preserves semen viability from 1 hour to 3 days.
Our pentent-pending SPX72 preservation fluid ensures true sample stability. Where most at-home samples degrade within 60–90 minutes and require inconvenient lab drop-off, we preserve viability to 72 hours.
Sapyen preserves semen viability from 1 hour to 3 days.
Our pentent-pending SPX72 preservation fluid ensures true sample stability. Where most at-home samples degrade within 60–90 minutes and require inconvenient lab drop-off, we preserve viability to 72 hours.
Motility preservation using SPX72 for 72 hours
| Motility | 0 Hours | 24 Hours | 48 Hours | 72 Hours |
|---|---|---|---|---|
| Control (%) | 73.48 | 31.8 | 0.44 | 0.04 |
| Sapyen (%) | 73.48 | 72.0 | 70.16 | 67.6 |
Total Motility results over 72 hours recorded at 0, 24, 48 & 72 hoursvg
Results reflect laboratory-conducted comparative studies involving over 100 semen samples assessed for motility, viability, and DNA fragmentation using SPX72 and commercially available transport media. Studies were performed under controlled conditions emulating mail-in environments across 24, 48, and 72 hours.
Other parameters remained stable and showed no change when tested over 72 hours
| Control | 0 Hours | 24 Hours | 48 Hours | 72 Hours |
|---|---|---|---|---|
| Concentration | 77.1 | 77.1 | 77.1 | 77.1 |
| Morphology | 4 | 4 | 4 | 4 |
| PH | 7.9 | 7.9 | 7.9 | 7.9 |
| DNA fragmentation | 12.4 | - | - | 12.4 |
Results reflect laboratory-conducted comparative studies involving over 100 semen samples assessed for motility, viability, and DNA fragmentation using SPX72 and commercially available transport media. Studies were performed under controlled conditions emulating mail-in environments across 24, 48, and 72 hours.
Clinician technical results
Sperm Motility Results over 24 hours
| Medium | pr | np | im | |
|---|---|---|---|---|
| Sapyen | SPX72 | 65.9 + 4.0 | 0.6 + 0.2 | 33.9 + 3.9 |
| Legacy/Fellow | Cryoprotectant medium | 25.4 + 6.1 | 3.1 + 0.4 | 72 + 5.8 |
| UK [Redacted] | 5% Glycerol | 19.9 + 4.9 | 5.4 + 1.2 | 75.6 + 4.7 |
| Malebox | 12% Glycerol | 10.5 + 3.9 | 7.4 + 0.9 | 81.6 + 3.8 |
Results reflect laboratory-conducted comparative studies involving over 100 semen samples assessed for motility, viability, and DNA fragmentation using SPX72 and commercially available transport media. Studies were performed under controlled conditions emulating mail-in environments across 24, 48, and 72 hours.
The only IVF-grade semen analysis and diagnostic test on the market.
Tests conducted:
- Core Semen Analysis (including Motility)
- DNA Fragmentation Index
- Antisperm Antibody
- DNA Methylation Testing
How does Sapyen compare?
| Fellow | Legacy | ||
|---|---|---|---|
Core Semen Analysis
including Motility
Based on online resources, including company websites; actual conditions may vary.
|
$149.00 | $229.00 | $295.00 |
DNA Fragmentation
|
$249.00 | $570.00 | |
DNA Methylation & Epigenetic Testing
|
$529.00 | ||
Post-Vasectomy Semen Analysis
Based on online resources, including company websites; actual conditions may vary.
|
$99.00 | $149.00 | $295.00 |
Accurate, Validated Test
Independent external validation data to assess similarity to in-lab analyses.
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Included
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IVF-Grade Semen Analysis
Sapyen tests are conducted at IVF labs by andrologists, evaluating debris, viscosity, FP, and aggregation/agglutination—unlike other tests.
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Included
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3-Day Sample Preservation & Stability
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Included
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US Availability in all 50 States
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Included
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Option to Test at Your Lab
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Included
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*$199 test with $30 shipping. **Predicts motility, results are not diagnostic. |
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*$199 test with $30 shipping.
**Predicts motility, results are not diagnostic.
A new era in semen analysis.
A new era in semen analysis.
Laboratory quality, not lab lookalike.
Sapyen tests are processed at certified fertility laboratories, not in-house facilities with no clinical accreditation — a common model used by other at-home providers.
Measured, not modeled.
Unlike competitors’ AI estimates, Sapyen measures sperm motility directly using WHO guidelines by trained clinical staff at IVF clinics nationwide.
Transparent pricing, no confusion.
Our core semen analysis test costs $149, more affordable than in-house and at-home testing options typically costing between $229 and $295.
Comprehensive analysis, not partial screening.
Many at-home kits assess only sperm count or basic motility. Sapyen offers full semen analysis, with optional DNA fragmentation, antisperm antibody, and sperm epigenetic and methylation testing.
Frequently Asked Questions
What does partnering with Sapyen look like?
Partnering with Sapyen means flexibility and support at every step. You can run tests through your own in-house lab to retain revenue, or use our accredited labs for a seamless process. Either way, your patients benefit from a more convenient, discreet experience that improves satisfaction and retention. We also provide comprehensive marketing resources, educational materials, and clinic training to help your team confidently integrate Sapyen into practice.
How does Sapyen support clinical workflows?
By reducing wait times, eliminating clinic collection rooms, and improving sample reliability, Sapyen helps streamline patient care while freeing up in-clinic resources.
Can patients use tests for diagnosis or planning?
Yes. Results can be integrated into clinical decision-making, including fertility assessments, treatment planning, and post-vasectomy confirmation.
How accurate are Sapyen test results?
Sapyen delivers lab-based accuracy by partnering with-certified labs and following the same testing standards trusted by fertility clinics worldwide. Every test measures key factors like sperm count, concentration, motility, morphology, and volume using proven analysis methods. Results are reviewed by trained specialists and benchmarked against World Health Organization guidelines. You’re not just getting numbers — you’re getting reliable, medically backed information you can act on.
How does Sapyen compare to clinic-based testing?
Sapyen offers the same lab-based accuracy you’d get at a fertility clinic — without the awkward waiting rooms, time off work, or clinical collection rooms. Our mail-to-lab process delivers clinical results discreetly, conveniently, and affordably, making quality reproductive care accessible to more men.
How does Sapyen compare to other at-home tests?
Sapyen sets the global standard for male reproductive health and at-home testing. We use a patent-pending transportation medium that preserves sample viability for 72 hours — far beyond industry norms. We’re the only test with FDA, TGA, and CE registration and endorsed by leading IVF clinics worldwide. At $149, our test is more affordable than competitors charging $200–$400.
How long are samples viable after collection?
Most clinics require semen samples within one hour. Sapyen’s SPX72 Preservation Technology keeps your sample viable for 72 hours, so you can collect at home and mail it in without losing accuracy.
Join the global thousands already using Sapyen.
Trusted by fertility specialists, urologists, and people just like you.
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