Sexually transmitted infections
Often present without symptoms
Semen Microbiome Test
Sapyen's Microbiome Test should be highly considered by anyone with unexplained infertility, abnormal semen analysis results, or a high DNA Fragmentation Index. Genital-tract infections are estimated to contribute to around 15% of male infertility, with the latest research suggesting that broader seminal microbiome imbalances may also influence sperm health. Where a standard semen analysis tells you what the sperm are doing, a microbiome test will go an important step further. It can identify a reason why your sperm function may be impaired, resulting in a more personalised fertility treatment and intervention plan.
Choose your Plan
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Free shippingBoth ways. Discreet packaging.
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Results in 7 business daysFrom sample send to lab to result
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ISO 9001:2015-certified labInternational reference laboratory partner
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WHAT WE TEST FOR
What's in the panel?
Your Sapyen Male Microbiome Test checks your semen sample for bacteria, yeast, sexually transmitted infections and viruses. We use a highly sensitive, DNA-based lab test to detect more precisely than older culture-based methods — to show you what's present, what matters and what your options are.
40+
microorganisms screened in one sample
Pathogen & Microflora Panel
35+ organisms across three categories
Pathogenic bacteria and fungal overgrowth trigger inflammation and oxidative stress in the reproductive tract — directly impacting motility, morphology and sperm DNA integrity. Identifying the specific organism means you and your doctor can treat the cause with targeted antibiotic or antifungal therapy.
Every bacterial and fungal species screened is named in full within your lab report — the categories above group them so they're easy to scan here.
Yeast & fungal organisms
Overgrowth can drive inflammation and oxidative stress
Normal microflora imbalance
May affect bacterial balance in the male reproductive tract
Extended Virus Panel
5 viruses linked to reduced sperm quality
Our extended viral screening identifies viruses that may be relevant to reproductive health and sperm quality.
HSV-1
Herpes Simplex Virus type 1
HSV-2
Herpes Simplex Virus type 2
EBV
Epstein–Barr Virus
CMV
Cytomegalovirus
HHV-6
Human Herpesvirus 6
WHY IT MATTERS
15% of male infertility is estimated to involve genital-tract infections.
Sapyen's Semen Microbiome Test provides a more detailed look at the semen microbiome, helping identify microorganisms that may be associated with sperm health and male infertility.
Often silent
Many of these infections cause no symptoms, so you can have one without knowing.
Harms sperm quality
They trigger inflammation and oxidative stress, affecting motility, morphology and sperm DNA integrity.
Treatable once named
Knowing the exact organism lets your doctor treat the cause with targeted antibiotic or antifungal therapy.
Protects your partner
Semen can carry bacteria between partners. Untreated infections are linked to endometritis and recurrent implantation failure.
WHEN TO TEST
Is this test right for you?
Your Test Results
An abnormal semen analysis, with reduced motility, morphology or count
A high Sperm DNA Fragmentation Index (DFI)
A diagnosis of unexplained infertility for you and your partner
Your History
Prostatitis or a previous genital-tract infection
An infection has been identified in your partner’s reproductive tract
A failed IVF or ICSI cycle, and you want to rule out an infection-related cause
Your Symptoms
Genital pain or swelling
Discharge
Painful urination
Discomfort during ejaculation
It's worth considering if any of these apply to you, your results or your history.
Our simple process
From order to answers.
01
Order Your Semen Microbiome Test Kit
Order online, no referral needed
02
Produce Your Sample
Choose the time and place that suits you.
03
Send to the Lab
We cover the postage cost.
04
Results available within 7 business days
Includes a clinician-ready summary.
Still have questions?
The things most people want to know first.
A molecular test that screens your semen sample for bacterial, fungal and viral infections — including STIs — that can affect sperm quality and fertility, and that a standard semen analysis doesn't check for.
More than 35 pathogens across sexually transmitted infections, yeast and normal microflora, plus an extended virus panel covering HSV-1, HSV-2, EBV, CMV and HHV-6.
Anyone with unexplained infertility, abnormal semen analysis results, a high DNA Fragmentation Index, a history of prostatitis or genital infection, relevant symptoms, or a partner with a reproductive-tract infection or recurrent implantation failure.
No — like all Sapyen tests, you can order directly online without a referral.
Within around 7 business days of your sample reaching the lab, through your secure Sapyen account — with a plain-English summary alongside the full report.
Your report flags the specific organism(s) identified, so you and your doctor can discuss targeted treatment — typically a course of antibiotics or antifungals — and whether your partner should also be tested.
Yes. Results are lab-issued and clinician-ready, so you can share them with your GP, urologist or fertility specialist.
Join the global thousands already using Sapyen.
Trusted by fertility specialists, urologists, and people just like you.
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